A similar manufacturing problem in Q4 2014 was not resolved until Q3 2015, when the former branded product Efcortesol was relaunched as the current generic. The previous licence holder, Amdipharm, has since been taken over by Concordia, a Canadian-headquartered generic drug producer.
Once the remaining warehoused stocks held by wholesalers and hospitals have been depleted, anyone who needs to renew their injection kit materials will have to ask their GP to issue a prescription for the alternative form of injectable hydrocortisone:
hydrocortisone sodium succinate (Solu-Cortef) 100mg powder, with a 2ml ampoule of solvent (sterile water) members outside the UK (Ireland, Europe and Americas) may also be able to obtain the Act-o-Vial preparation, containing hydrocortisone sodium succinate and water in a chambered ampoule.
Video instructions for how to prepare the Solu-Cortef powder and water can be viewed online and written guidance is also available on the website here...
Guidance for GPs on what to prescribe can be found in the ADSHG’s GP Care leaflet. GPs are reminded that none of the alternative liquid injectable steroid preparations, eg Hydrocortistab (hydrocortisone acetate) are suitable for emergency use, being slow-acting preparations for joint injections.
The Department of Health's Medicines Supply team is aware of the issue and in contact with both Concordia and Pfizer. It is closely monitoring the situation and has notified Clinical Commissioning Groups of this shortage. The team has commissioned the following guidance which you can read on this link.
As any further information becomes available, we will update members in the member-only online forum.
- Read more...
- 2,418 views